Nueva publicación en la que participa el Grupo MICROBIO en la revista “Membranes”
- Publicado por: Adolfo Martínez
- 16 julio 2020
- Comentarios desactivados
Artículo original que lleva por título: “Evaluation of an integrated ultrafiltration/solid phase extraction process for purification of oligomeric grape seed procyanidins”. Membranes, 10 (7), 147.
Publicado en la revista de acceso libre Membranes (Factor de Impacto 3.094) de la editorial MDPI, dentro del número especial “Integrated membrane systems and processes” editado por los Profesores Dr. Alfredo Cassano y el Dr. Alberto Figoli.
ABSTRACT: The effectiveness of a preparative integrated ultrafiltration/solid-phase extraction (UF/SPE) process for purification of oligomeric procyanidins (OPCs) from a crude grape seed extract (GSE) was studied for the first time. The separation of OPCs from polymeric procyanidins (PPCs) by UF was very efficient. The membrane showed an acceptable filtration flux of 6 to 3.5 L/h·m2 at 0.5 bar of transmembrane pressure and 95% recovery of its water flux after chemical cleaning. The process was scalable to a pilot scale. The separation of very polar and ionic species from OPCs by SPE (XAD7HP and XAD16 resins) was also very good, but both adsorbents lost their retention capacities quickly, due probably to irreversible retention of OPCs/PPCs. Even though the global purification of OPCs by the integrated UF/SPE process allowed the recovery of 24.2 g of highly purified OPCs (83% purity) from 14.4 L of crude grape seed extract, the use of these adsorbents for further purification of the OPCs was very limited.